Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRN58299.1Two component transcriptional regulator. (225 aa)    
Predicted Functional Partners:
KRN58298.1
Integral membrane sensor signal transduction histidine kinase.
 0.998
KRN58296.1
ABC superfamily ATP binding cassette transporter permease and substrate binding protein.
 
     0.893
KRN58297.1
ABC superfamily ATP binding cassette transporter, ABC protein.
 
   
 0.883
KRN58579.1
Multi-sensor signal transduction histidine kinase.
 
 0.842
KRN59149.1
Phosphate regulon sensor kinase PhoR.
 
 0.839
KRN58377.1
Two-component system histidine kinase.
 
 0.825
KRN58644.1
Phosphate regulon sensor kinase PhoR.
 0.822
KRN59496.1
Two-component histidine kinase.
 
 0.724
sigA
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.630
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.623
Your Current Organism:
Lactobacillus secaliphilus
NCBI taxonomy Id: 396268
Other names: CCUG 53218, DSM 17896, JCM 15613, L. secaliphilus, Lactobacillus secaliphilus Ehrmann et al. 2007
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