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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN58447.1Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (363 aa)    
Predicted Functional Partners:
KRN58171.1
Homoserine dehydrogenase Hdh.
  
 0.995
KRN58592.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.990
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.983
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 0.819
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.723
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 
 0.706
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.681
guaA
GMP synthase domain-containing protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.666
KRN59528.1
Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.638
KRN59576.1
Acetaldehyde dehydrogenase (acetylating); In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
 0.573
Your Current Organism:
Lactobacillus secaliphilus
NCBI taxonomy Id: 396268
Other names: CCUG 53218, DSM 17896, JCM 15613, L. secaliphilus, Lactobacillus secaliphilus Ehrmann et al. 2007
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