Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addARecombination helicase AddA; ATP-dependent DNA helicase. (1273 aa)    
Predicted Functional Partners:
KRN58589.1
ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
 
 
 0.999
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.899
KRN58739.1
single-stranded-DNA-specific exonuclease RecJ.
     
 0.858
KRN58220.1
ATP-dependent DNA helicase PcrA.
 
  
0.845
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.793
recD2
Exodeoxyribonuclease V, alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.759
KRN58836.1
Hypothetical protein.
 
     0.756
KRN58591.1
Glycerophosphoryl diester phosphodiesterase.
       0.705
KRN58703.1
Hypothetical protein.
  
 
 0.701
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
     
 0.686
Your Current Organism:
Lactobacillus secaliphilus
NCBI taxonomy Id: 396268
Other names: CCUG 53218, DSM 17896, JCM 15613, L. secaliphilus, Lactobacillus secaliphilus Ehrmann et al. 2007
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