Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tgr7_1237KEGG: tcx:Tcr_0501 coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (465 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.959
hemF
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.956
Tgr7_2413
PFAM: conserved hypothetical protein; KEGG: mfa:Mfla_0474 hypothetical protein.
    
 0.915
Tgr7_2534
KEGG: vch:VCA0867 outer membrane protein W.
 
  
 0.890
Tgr7_2738
PFAM: beta-lactamase domain protein; KEGG: pmy:Pmen_1128 beta-lactamase domain-containing protein.
  
    0.833
Tgr7_0631
KEGG: aeh:Mlg_1882 cytochrome c oxidase, cbb3-type, subunit I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.701
Tgr7_3000
KEGG: tbd:Tbd_0338 cytochrome c oxidase cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.691
Tgr7_0632
TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; PFAM: cytochrome C oxidase mono-heme subunit/FixO; KEGG: pmy:Pmen_2600 cytochrome c oxidase, cbb3-type, subunit II.
 
  
 0.644
Tgr7_0636
TIGRFAM: cytochrome c oxidase accessory protein CcoG; KEGG: aeh:Mlg_1877 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
  
 0.644
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.640
Your Current Organism:
Thioalkalivibrio sulfidiphilus
NCBI taxonomy Id: 396588
Other names: T. sulfidiphilus HL-EbGr7, Thioalkalivibrio sp. HL-EbGR7, Thioalkalivibrio sulfidiphilus HL-EbGr7, Thioalkalivibrio sulfidiphilus str. HL-EbGr7, Thioalkalivibrio sulfidiphilus strain HL-EbGr7, Thioalkalivibrio sulfidophilus HL-EbGr7
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