node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK90_0489 | TK90_0492 | TK90_0489 | TK90_0492 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | 0.565 |
TK90_0489 | TK90_0493 | TK90_0489 | TK90_0493 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | KEGG: noc:Noc_0337 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding lysin domain; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | 0.656 |
TK90_0489 | miaA | TK90_0489 | TK90_0495 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.505 |
TK90_0489 | nnrD | TK90_0489 | TK90_0491 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.654 |
TK90_0489 | polA | TK90_0489 | TK90_0044 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.500 |
TK90_0489 | queG | TK90_0489 | TK90_0490 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.582 |
TK90_0489 | tsaD | TK90_0489 | TK90_0154 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.446 |
TK90_0492 | TK90_0489 | TK90_0492 | TK90_0489 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | 0.565 |
TK90_0492 | TK90_0493 | TK90_0492 | TK90_0493 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | KEGG: noc:Noc_0337 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding lysin domain; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | 0.742 |
TK90_0492 | TK90_1294 | TK90_0492 | TK90_1294 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | PFAM: peptidase M22 glycoprotease; KEGG: xcv:XCV3238 glycoprotease family protein. | 0.973 |
TK90_0492 | TK90_2299 | TK90_0492 | TK90_2299 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | PFAM: aminoglycoside phosphotransferase; KEGG: rru:Rru_A3437 aminoglycoside phosphotransferase. | 0.586 |
TK90_0492 | miaA | TK90_0492 | TK90_0495 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.708 |
TK90_0492 | nnrD | TK90_0492 | TK90_0491 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.953 |
TK90_0492 | polA | TK90_0492 | TK90_0044 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.554 |
TK90_0492 | queG | TK90_0492 | TK90_0490 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.694 |
TK90_0492 | trmD | TK90_0492 | TK90_0429 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.534 |
TK90_0492 | tsaD | TK90_0492 | TK90_0154 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.898 |
TK90_0493 | TK90_0489 | TK90_0493 | TK90_0489 | KEGG: noc:Noc_0337 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding lysin domain; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. | 0.656 |
TK90_0493 | TK90_0492 | TK90_0493 | TK90_0492 | KEGG: noc:Noc_0337 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding lysin domain; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | 0.742 |
TK90_0493 | miaA | TK90_0493 | TK90_0495 | KEGG: noc:Noc_0337 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding lysin domain; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.813 |