STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TK90_1366PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (176 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.783
TK90_1262
KEGG: mca:MCA1789 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.743
htpG
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
  
 
 0.600
TK90_1365
PFAM: Protein of unknown function DUF2235; KEGG: son:SO_3711 hypothetical protein.
       0.547
TK90_1367
PFAM: Rhomboid family protein; KEGG: aci:ACIAD1051 hypothetical protein.
       0.528
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.492
TK90_1856
TIGRFAM: glutaredoxin-family domain protein; PFAM: Redoxin domain protein; glutaredoxin; KEGG: vpa:VP2753 peroxiredoxin family protein/glutaredoxin.
  
  
 0.489
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.483
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 
 0.483
TK90_1364
PFAM: Metal-dependent hydrolase HDOD; Serine/threonine-protein kinase-like domain; GAF domain protein; SMART: GAF domain protein; KEGG: tmz:Tmz1t_1797 serine/threonine protein kinase.
  
 
 0.463
Your Current Organism:
Thioalkalivibrio sp. K90mix
NCBI taxonomy Id: 396595
Other names: T. sp. K90mix
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.