close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TK90_1663KEGG: kra:Krad_3541 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (491 aa)    
Predicted Functional Partners:
TK90_1403
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: mms:mma_0597 hypothetical protein.
   0.837
TK90_1994
KEGG: har:HEAR2987 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
    0.770
TK90_1385
Signal transduction protein containing sensor and EAL domains-like protein; KEGG: hypothetical protein LOC100014949.
 
     0.750
TK90_0533
KEGG: hna:Hneap_2065 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; response regulator receiver; GGDEF domain containing protein; SMART: EAL domain protein; response regulator receiver.
  
 0.748
TK90_1099
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: pmy:Pmen_0619 response regulator receiver modulated diguanylate cyclase/phosphodiesterase.
 
   0.745
TK90_2318
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: aeh:Mlg_2042 diguanylate phosphodiesterase.
 
    0.740
TK90_0680
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: azo:azo3381 signaling protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; response regulator receiver; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; GAF domain protein.
 
0.640
TK90_0489
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
0.608
TK90_1026
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein.
 
 
0.608
TK90_1662
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: dps:DP1549 TetR transcription regulator.
   
   0.526
Your Current Organism:
Thioalkalivibrio sp. K90mix
NCBI taxonomy Id: 396595
Other names: T. sp. K90mix
Server load: medium (78%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.