node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK90_1366 | clpB | TK90_1366 | TK90_2032 | PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.783 |
TK90_1366 | dnaK | TK90_1366 | TK90_0460 | PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.483 |
TK90_1366 | grpE | TK90_1366 | TK90_0459 | PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.492 |
TK90_1366 | hscA | TK90_1366 | TK90_0834 | PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.483 |
TK90_1366 | htpG | TK90_1366 | TK90_0435 | PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. | 0.600 |
TK90_2477 | TK90_2478 | TK90_2477 | TK90_2478 | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | 0.623 |
TK90_2477 | clpB | TK90_2477 | TK90_2032 | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.785 |
TK90_2477 | dnaK | TK90_2477 | TK90_0460 | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.483 |
TK90_2477 | grpE | TK90_2477 | TK90_0459 | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.492 |
TK90_2477 | hscA | TK90_2477 | TK90_0834 | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.483 |
TK90_2477 | htpG | TK90_2477 | TK90_0435 | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. | 0.600 |
TK90_2478 | TK90_2477 | TK90_2478 | TK90_2477 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.623 |
TK90_2478 | clpB | TK90_2478 | TK90_2032 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.717 |
TK90_2478 | clpP | TK90_2478 | TK90_0573 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.469 |
TK90_2478 | dnaK | TK90_2478 | TK90_0460 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.975 |
TK90_2478 | grpE | TK90_2478 | TK90_0459 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.929 |
TK90_2478 | hscA | TK90_2478 | TK90_0834 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.946 |
TK90_2478 | htpG | TK90_2478 | TK90_0435 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_3102 curved DNA-binding protein. | ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. | 0.922 |
clpB | TK90_1366 | TK90_2032 | TK90_1366 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein Hsp20; KEGG: sfu:Sfum_2860 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | 0.783 |
clpB | TK90_2477 | TK90_2032 | TK90_2477 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein Hsp20; KEGG: mca:MCA2532 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.785 |