Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TK90_2425KEGG: hch:HCH_06361 hypothetical protein. (150 aa)    
Predicted Functional Partners:
TK90_2473
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.713
TK90_2366
Membrane protein-like protein; KEGG: aha:AHA_1688 hypothetical protein.
  
     0.678
TK90_2426
PFAM: protein of unknown function YGGT; KEGG: aeh:Mlg_0339 protein of unknown function YGGT.
       0.630
TK90_1183
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: pfo:Pfl01_1571 CheW protein.
  
     0.567
TK90_2217
PFAM: cytochrome c1; KEGG: noc:Noc_0297 cytochrome c1.
  
     0.534
TK90_0554
PFAM: Protein of unknown function DUF2066; KEGG: hha:Hhal_0709 hypothetical protein.
  
     0.519
TK90_2111
PFAM: RDD domain containing protein; KEGG: vap:Vapar_2364 RDD domain containing protein.
  
     0.508
TK90_0040
PFAM: cytochrome c class I; KEGG: aeh:Mlg_2853 cytochrome c, class I.
  
     0.485
TK90_1760
PFAM: Domain of unknown function DUF1791; KEGG: tbd:Tbd_1053 hypothetical protein.
  
     0.467
TK90_1822
PFAM: protein of unknown function UPF0149; KEGG: aeh:Mlg_2541 YecA family protein; Belongs to the UPF0149 family.
  
     0.444
Your Current Organism:
Thioalkalivibrio sp. K90mix
NCBI taxonomy Id: 396595
Other names: T. sp. K90mix
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