STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIHG_05980GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (385 aa)    
Predicted Functional Partners:
CIHG_07438
GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
    
 
0.955
CIHG_05157
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
  
 
0.951
CIHG_07698
RTR1-type domain-containing protein.
    
 
 0.943
CIHG_03802
DNA-directed RNA polymerase II subunit RPB3.
   
 
 0.923
CIHG_00413
DNA-directed RNA polymerases I.
   
 
 0.916
CIHG_04077
DNA-directed RNA polymerases I and III subunit RPAC1.
   
 
 0.899
CIHG_09031
DNA-directed RNA polymerase II subunit RPB2; Belongs to the RNA polymerase beta chain family.
   
 
 0.895
CIHG_09030
DNA-directed RNA polymerase II subunit RPB2.
   
 
 0.895
CIHG_07643
RNA polymerase II subunit 7.
   
 
 0.881
CIHG_09289
RNA_pol_L_2 domain-containing protein.
    
 
 0.881
Your Current Organism:
Coccidioides immitis H5384
NCBI taxonomy Id: 396776
Other names: C. immitis H538.4, Coccidioides immitis H538.4
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.