Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORB25157.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)    
Predicted Functional Partners:
nrdE
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.916
nrdI
Ribonucleotide reductase assembly protein NrdI; Probably involved in ribonucleotide reductase function.
  
  
 0.756
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.682
ORB25158.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.645
ORB25159.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family.
     
 0.638
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.616
ORB25155.1
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.593
ORB25151.1
DUF3093 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.581
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.572
ORB25154.1
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
       0.571
Your Current Organism:
Mycolicibacterium moriokaense
NCBI taxonomy Id: 39691
Other names: ATCC 43059, CCUG 37671, CIP 105393, DSM 44221, JCM 6375, M. moriokaense, Mycobacterium moriokaense, NCH E11715
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