Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. (286 aa)    
Predicted Functional Partners:
ORB31160.1
CCA tRNA nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.575
ORB28462.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.575
ORB28463.1
GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.542
ORB28245.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.527
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.446
ORB31144.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.438
ORB27644.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.433
ORB31704.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.430
ORB27657.1
Alpha-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.429
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.427
Your Current Organism:
Mycolicibacterium parafortuitum
NCBI taxonomy Id: 39692
Other names: ATCC 19686, CCUG 20999, CIP 106802, DSM 43528, JCM 6367, M. parafortuitum, Mycobacterium parafortuitum, NCTC 10411, NRRL B-4035
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