STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB26998.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)    
Predicted Functional Partners:
ORB28425.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.727
gyrB
DNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]
   
 
 0.719
ORB30228.1
DNA gyrase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.719
ORB29404.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.704
ORB30464.1
Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.630
ORB31674.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.625
ORB32094.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.625
ORB25271.1
Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.625
ORB32407.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.599
ORB31919.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.599
Your Current Organism:
Mycolicibacterium parafortuitum
NCBI taxonomy Id: 39692
Other names: ATCC 19686, CCUG 20999, CIP 106802, DSM 43528, JCM 6367, M. parafortuitum, Mycobacterium parafortuitum, NCTC 10411, NRRL B-4035
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.