STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB43642.1Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)    
Predicted Functional Partners:
ORB38298.1
Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
ORB34231.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.722
BST41_27105
Pyruvate kinase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.721
ORB40194.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.527
ORB40046.1
Bifunctional diguanylate cyclase/phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.512
aspA-2
Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.464
glnD
[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.460
BST41_33510
Hypothetical protein; Frameshifted; incomplete; missing start and stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.451
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
       0.428
ORB34336.1
Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.421
Your Current Organism:
Mycolicibacterium porcinum
NCBI taxonomy Id: 39693
Other names: ATCC 33776, CCUG 37674, CIP 105392, DSM 44242, JCM 6378, M. porcinum, Mycobacterium porcinum, strain E10241-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.