STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (290 aa)    
Predicted Functional Partners:
ORB40704.1
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.942
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.890
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.883
ORB40703.1
1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.837
ORB36686.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.835
ORB34724.1
Prolyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.835
ORB39591.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S33 family.
    
  0.756
ORB44650.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.711
ORB41295.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
BST41_27105
Pyruvate kinase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.706
Your Current Organism:
Mycolicibacterium porcinum
NCBI taxonomy Id: 39693
Other names: ATCC 33776, CCUG 37674, CIP 105392, DSM 44242, JCM 6378, M. porcinum, Mycobacterium porcinum, strain E10241-1
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