STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB41374.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)    
Predicted Functional Partners:
ORB41375.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.967
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 0.901
ORB37772.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.814
ORB44567.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.754
atpF
F0F1 ATP synthase subunit B/delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family.
  
 
 0.753
ORB38595.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.740
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
   
 0.726
ORB41373.1
Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.718
ORB36346.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.715
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.714
Your Current Organism:
Mycolicibacterium porcinum
NCBI taxonomy Id: 39693
Other names: ATCC 33776, CCUG 37674, CIP 105392, DSM 44242, JCM 6378, M. porcinum, Mycobacterium porcinum, strain E10241-1
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