STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORB37282.1Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
ORB40734.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.875
ORB37283.1
PucR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.788
ORB44900.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.
    
 0.742
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.742
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.741
ORB35215.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family.
   
 0.741
ORB37284.1
Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.703
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
   0.643
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
   0.633
ORB34988.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.626
Your Current Organism:
Mycolicibacterium porcinum
NCBI taxonomy Id: 39693
Other names: ATCC 33776, CCUG 37674, CIP 105392, DSM 44242, JCM 6378, M. porcinum, Mycobacterium porcinum, strain E10241-1
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