Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
katGCatalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (732 aa)    
Predicted Functional Partners:
ORB34251.1
Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.959
ORB41387.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
     
 0.958
ORB36512.1
Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
 
  
 0.882
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.880
ORB45056.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.878
ORB37648.1
Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
    
 0.878
ORB37404.1
Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
 
  
 0.867
hisC
Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.847
ORB44540.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.840
pat
Histidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
     
 0.840
Your Current Organism:
Mycolicibacterium porcinum
NCBI taxonomy Id: 39693
Other names: ATCC 33776, CCUG 37674, CIP 105392, DSM 44242, JCM 6378, M. porcinum, Mycobacterium porcinum, strain E10241-1
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