C807_00263 protein (Lachnospiraceae bacterium 284)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

C807_00263

C_GCAxxG_C_C family protein. (151 aa)

Predicted Functional Partners:

C807_00939

0.888

thyA

0.845

C807_00262

0.781

C807_03200

0.616

fhs

0.555

C807_01096

0.549

purD

0.546

tmk

0.545

folD

0.538

C807_01477

0.537

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_00262	C807_00263	C807_00262	C807_00263	Hypothetical protein.	C_GCAxxG_C_C family protein.	0.781
C807_00263	C807_00262	C807_00263	C807_00262	C_GCAxxG_C_C family protein.	Hypothetical protein.	0.781
C807_00263	C807_00939	C807_00263	C807_00939	C_GCAxxG_C_C family protein.	Methionine synthase.	0.888
C807_00263	C807_01096	C807_00263	C807_01096	C_GCAxxG_C_C family protein.	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.549
C807_00263	C807_01477	C807_00263	C807_01477	C_GCAxxG_C_C family protein.	Hypothetical protein.	0.537
C807_00263	C807_03200	C807_00263	C807_03200	C_GCAxxG_C_C family protein.	dCMP deaminase.	0.616
C807_00263	fhs	C807_00263	C807_01289	C_GCAxxG_C_C family protein.	Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.	0.555
C807_00263	folD	C807_00263	C807_01288	C_GCAxxG_C_C family protein.	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.538
C807_00263	purD	C807_00263	C807_01379	C_GCAxxG_C_C family protein.	Phosphoribosylamine-glycine ligase; Belongs to the GARS family.	0.546
C807_00263	thyA	C807_00263	C807_01670	C_GCAxxG_C_C family protein.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.845
C807_00263	tmk	C807_00263	C807_03013	C_GCAxxG_C_C family protein.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.545
C807_00939	C807_00263	C807_00939	C807_00263	Methionine synthase.	C_GCAxxG_C_C family protein.	0.888
C807_00939	C807_01477	C807_00939	C807_01477	Methionine synthase.	Hypothetical protein.	0.901
C807_00939	fhs	C807_00939	C807_01289	Methionine synthase.	Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.	0.982
C807_00939	folD	C807_00939	C807_01288	Methionine synthase.	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.888
C807_00939	purD	C807_00939	C807_01379	Methionine synthase.	Phosphoribosylamine-glycine ligase; Belongs to the GARS family.	0.612
C807_00939	thyA	C807_00939	C807_01670	Methionine synthase.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.746
C807_01096	C807_00263	C807_01096	C807_00263	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	C_GCAxxG_C_C family protein.	0.549
C807_01096	C807_03200	C807_01096	C807_03200	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	dCMP deaminase.	0.962
C807_01096	thyA	C807_01096	C807_01670	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.988