nnrE protein (Lachnospiraceae bacterium 284)

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nnrE

YjeF family domain-containing protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] (522 aa)

Predicted Functional Partners:

C807_00912

0.996

C807_00893

0.990

C807_01001

0.990

C807_01298

0.885

C807_03682

0.869

C807_01626

0.815

C807_02744

0.815

nadE

0.814

C807_02952

0.790

groL

0.749

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_00893	C807_00912	C807_00893	C807_00912	Hypothetical protein.	Hypothetical protein; Belongs to the DEAD box helicase family.	0.971
C807_00893	nadE	C807_00893	C807_03723	Hypothetical protein.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.919
C807_00893	nnrE	C807_00893	C807_01299	Hypothetical protein.	YjeF family domain-containing protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]	0.990
C807_00912	C807_00893	C807_00912	C807_00893	Hypothetical protein; Belongs to the DEAD box helicase family.	Hypothetical protein.	0.971
C807_00912	C807_01001	C807_00912	C807_01001	Hypothetical protein; Belongs to the DEAD box helicase family.	Hypothetical protein.	0.975
C807_00912	C807_01626	C807_00912	C807_01626	Hypothetical protein; Belongs to the DEAD box helicase family.	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	0.877
C807_00912	C807_02952	C807_00912	C807_02952	Hypothetical protein; Belongs to the DEAD box helicase family.	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	0.877
C807_00912	groL	C807_00912	C807_01759	Hypothetical protein; Belongs to the DEAD box helicase family.	Chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.411
C807_00912	nnrE	C807_00912	C807_01299	Hypothetical protein; Belongs to the DEAD box helicase family.	YjeF family domain-containing protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]	0.996
C807_01001	C807_00912	C807_01001	C807_00912	Hypothetical protein.	Hypothetical protein; Belongs to the DEAD box helicase family.	0.975
C807_01001	nadE	C807_01001	C807_03723	Hypothetical protein.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.919
C807_01001	nnrE	C807_01001	C807_01299	Hypothetical protein.	YjeF family domain-containing protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]	0.990
C807_01298	C807_03682	C807_01298	C807_03682	Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.	YjeE family ATPase.	0.793
C807_01298	nadE	C807_01298	C807_03723	Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.595
C807_01298	nnrE	C807_01298	C807_01299	Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.	YjeF family domain-containing protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]	0.885
C807_01626	C807_00912	C807_01626	C807_00912	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Hypothetical protein; Belongs to the DEAD box helicase family.	0.877
C807_01626	C807_02744	C807_01626	C807_02744	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Pyruvate:ferredoxin (flavodoxin) oxidoreductase.	0.510
C807_01626	nnrE	C807_01626	C807_01299	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	YjeF family domain-containing protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]	0.815
C807_02744	C807_01626	C807_02744	C807_01626	Pyruvate:ferredoxin (flavodoxin) oxidoreductase.	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	0.510
C807_02744	C807_02952	C807_02744	C807_02952	Pyruvate:ferredoxin (flavodoxin) oxidoreductase.	RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	0.510

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