C807_01375 protein (Lachnospiraceae bacterium 284)

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Score

C807_01375

ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. (818 aa)

Predicted Functional Partners:

C807_00234

0.960

dnaK

0.960

C807_03908

0.946

clpP-2

0.905

grpE

0.904

clpP

0.903

C807_03206

0.886

C807_04032

0.885

C807_01291

0.883

dnaJ

0.880

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_00234	C807_01291	C807_00234	C807_01291	Hypothetical protein; Belongs to the heat shock protein 70 family.	Hypothetical protein.	0.600
C807_00234	C807_01375	C807_00234	C807_01375	Hypothetical protein; Belongs to the heat shock protein 70 family.	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	0.960
C807_00234	C807_04032	C807_00234	C807_04032	Hypothetical protein; Belongs to the heat shock protein 70 family.	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Belongs to the peptidase S14 family.	0.632
C807_00234	clpP	C807_00234	C807_00221	Hypothetical protein; Belongs to the heat shock protein 70 family.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.678
C807_00234	clpP-2	C807_00234	C807_01500	Hypothetical protein; Belongs to the heat shock protein 70 family.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.632
C807_00234	dnaJ	C807_00234	C807_02418	Hypothetical protein; Belongs to the heat shock protein 70 family.	Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...]	0.997
C807_00234	grpE	C807_00234	C807_02420	Hypothetical protein; Belongs to the heat shock protein 70 family.	Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]	0.993
C807_01291	C807_00234	C807_01291	C807_00234	Hypothetical protein.	Hypothetical protein; Belongs to the heat shock protein 70 family.	0.600
C807_01291	C807_01375	C807_01291	C807_01375	Hypothetical protein.	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	0.883
C807_01291	C807_03908	C807_01291	C807_03908	Hypothetical protein.	Hypothetical protein.	0.544
C807_01291	dnaJ	C807_01291	C807_02418	Hypothetical protein.	Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...]	0.487
C807_01291	dnaK	C807_01291	C807_02419	Hypothetical protein.	Chaperone dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.600
C807_01291	grpE	C807_01291	C807_02420	Hypothetical protein.	Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]	0.656
C807_01375	C807_00234	C807_01375	C807_00234	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	Hypothetical protein; Belongs to the heat shock protein 70 family.	0.960
C807_01375	C807_01291	C807_01375	C807_01291	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	Hypothetical protein.	0.883
C807_01375	C807_03206	C807_01375	C807_03206	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	Hypothetical protein.	0.886
C807_01375	C807_03908	C807_01375	C807_03908	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	Hypothetical protein.	0.946
C807_01375	C807_04032	C807_01375	C807_04032	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Belongs to the peptidase S14 family.	0.885
C807_01375	clpP	C807_01375	C807_00221	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.903
C807_01375	clpP-2	C807_01375	C807_01500	ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.905