close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C807_01755RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (773 aa)    
Predicted Functional Partners:
C807_00190
Hypothetical protein.
  
 
 0.976
C807_02744
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
  0.975
C807_03630
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.951
C807_00939
Methionine synthase.
    
 0.949
C807_01808
Hypothetical protein.
  
 
 0.949
C807_01418
Hypothetical protein.
  
 
 0.947
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.945
C807_01389
Anaerobic ribonucleoside-triphosphate reductase.
     
 0.942
C807_00945
Hypothetical protein.
  
 
 0.936
C807_01098
Anaerobic ribonucleoside-triphosphate reductase.
     
 0.931
Your Current Organism:
Lachnospiraceae bacterium 284
NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.