sfsA protein (Lachnospiraceae bacterium 284)

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Score

sfsA

A/G-specific adenine glycosylase; Belongs to the SfsA family. (599 aa)

Predicted Functional Partners:

C807_03406

0.987

C807_00899

0.848

C807_01895

0.773

C807_03452

0.746

C807_01897

0.718

nth

0.623

nth-2

0.623

C807_00874

0.523

C807_01388

0.523

C807_03001

0.510

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_00874	sfsA	C807_00874	C807_01896	Hypothetical protein; Belongs to the Nudix hydrolase family.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.523
C807_00899	C807_03406	C807_00899	C807_03406	DNA-deoxyinosine glycosylase.	Exodeoxyribonuclease III (xth).	0.922
C807_00899	sfsA	C807_00899	C807_01896	DNA-deoxyinosine glycosylase.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.848
C807_01388	sfsA	C807_01388	C807_01896	Hypothetical protein.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.523
C807_01895	C807_01897	C807_01895	C807_01897	Hypothetical protein.	Hypothetical protein.	0.718
C807_01895	sfsA	C807_01895	C807_01896	Hypothetical protein.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.773
C807_01897	C807_01895	C807_01897	C807_01895	Hypothetical protein.	Hypothetical protein.	0.718
C807_01897	sfsA	C807_01897	C807_01896	Hypothetical protein.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.718
C807_03001	sfsA	C807_03001	C807_01896	Hypothetical protein.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.510
C807_03406	C807_00899	C807_03406	C807_00899	Exodeoxyribonuclease III (xth).	DNA-deoxyinosine glycosylase.	0.922
C807_03406	C807_03452	C807_03406	C807_03452	Exodeoxyribonuclease III (xth).	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.991
C807_03406	nth	C807_03406	C807_01227	Exodeoxyribonuclease III (xth).	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.996
C807_03406	nth-2	C807_03406	C807_02591	Exodeoxyribonuclease III (xth).	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.984
C807_03406	sfsA	C807_03406	C807_01896	Exodeoxyribonuclease III (xth).	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.987
C807_03452	C807_03406	C807_03452	C807_03406	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III (xth).	0.991
C807_03452	sfsA	C807_03452	C807_01896	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.746
nth	C807_03406	C807_01227	C807_03406	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	Exodeoxyribonuclease III (xth).	0.996
nth	sfsA	C807_01227	C807_01896	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.623
nth-2	C807_03406	C807_02591	C807_03406	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	Exodeoxyribonuclease III (xth).	0.984
nth-2	sfsA	C807_02591	C807_01896	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	A/G-specific adenine glycosylase; Belongs to the SfsA family.	0.623