close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C807_02166Hypothetical protein. (307 aa)    
Predicted Functional Partners:
C807_02165
Hypothetical protein.
     0.989
C807_02061
HsdR family type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
 
 0.832
C807_03337
HsdR family type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
 
 0.832
C807_01749
Hypothetical protein.
  
 
 0.822
C807_02063
Hypothetical protein.
  
 
 0.822
C807_03339
Type I restriction enzyme, S subunit.
  
 
 0.822
C807_03340
Hypothetical protein.
  
 
 0.822
C807_02167
Hypothetical protein.
       0.718
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
    
 
 0.534
C807_02872
Hypothetical protein.
    
   0.504
Your Current Organism:
Lachnospiraceae bacterium 284
NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4
Server load: low (24%) [HD]