phnW protein (Lachnospiraceae bacterium 284)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

phnW

2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (380 aa)

Predicted Functional Partners:

C807_02172

0.967

C807_00939

0.934

C807_00831

0.910

C807_02766

0.910

glyA

0.901

C807_01563

0.899

C807_01298

0.876

C807_01629

0.875

C807_02814

0.861

C807_02813

0.773

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_00831	C807_00939	C807_00831	C807_00939	Threonine ammonia-lyase.	Methionine synthase.	0.969
C807_00831	C807_01563	C807_00831	C807_01563	Threonine ammonia-lyase.	Hypothetical protein.	0.969
C807_00831	C807_01629	C807_00831	C807_01629	Threonine ammonia-lyase.	Serine O-acetyltransferase.	0.938
C807_00831	C807_02172	C807_00831	C807_02172	Threonine ammonia-lyase.	Phosphonopyruvate decarboxylase.	0.681
C807_00831	C807_02766	C807_00831	C807_02766	Threonine ammonia-lyase.	Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.890
C807_00831	glyA	C807_00831	C807_01892	Threonine ammonia-lyase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.952
C807_00831	phnW	C807_00831	C807_02815	Threonine ammonia-lyase.	2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.910
C807_00939	C807_00831	C807_00939	C807_00831	Methionine synthase.	Threonine ammonia-lyase.	0.969
C807_00939	C807_01629	C807_00939	C807_01629	Methionine synthase.	Serine O-acetyltransferase.	0.876
C807_00939	C807_02766	C807_00939	C807_02766	Methionine synthase.	Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.456
C807_00939	glyA	C807_00939	C807_01892	Methionine synthase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.958
C807_00939	phnW	C807_00939	C807_02815	Methionine synthase.	2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.934
C807_01298	phnW	C807_01298	C807_02815	Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.	2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.876
C807_01563	C807_00831	C807_01563	C807_00831	Hypothetical protein.	Threonine ammonia-lyase.	0.969
C807_01563	glyA	C807_01563	C807_01892	Hypothetical protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.960
C807_01563	phnW	C807_01563	C807_02815	Hypothetical protein.	2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.899
C807_01629	C807_00831	C807_01629	C807_00831	Serine O-acetyltransferase.	Threonine ammonia-lyase.	0.938
C807_01629	C807_00939	C807_01629	C807_00939	Serine O-acetyltransferase.	Methionine synthase.	0.876
C807_01629	glyA	C807_01629	C807_01892	Serine O-acetyltransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.939
C807_01629	phnW	C807_01629	C807_02815	Serine O-acetyltransferase.	2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.875

page 1 of 3

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About