C807_03200 protein (Lachnospiraceae bacterium 284)

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Score

C807_03200

dCMP deaminase. (159 aa)

Predicted Functional Partners:

C807_01096

0.962

thyA

0.955

tmk

0.947

C807_00634

0.934

cmk

0.932

upp

0.825

C807_03202

0.658

C807_00620

0.654

C807_03203

0.646

C807_00263

0.616

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_00263	C807_00634	C807_00263	C807_00634	C_GCAxxG_C_C family protein.	Hypothetical protein; Belongs to the 5'-nucleotidase family.	0.469
C807_00263	C807_01096	C807_00263	C807_01096	C_GCAxxG_C_C family protein.	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.549
C807_00263	C807_03200	C807_00263	C807_03200	C_GCAxxG_C_C family protein.	dCMP deaminase.	0.616
C807_00263	C807_03202	C807_00263	C807_03202	C_GCAxxG_C_C family protein.	RpiB/LacA/LacB family sugar-phosphate isomerase.	0.503
C807_00263	thyA	C807_00263	C807_01670	C_GCAxxG_C_C family protein.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.845
C807_00263	tmk	C807_00263	C807_03013	C_GCAxxG_C_C family protein.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.545
C807_00620	C807_03200	C807_00620	C807_03200	Hypothetical protein.	dCMP deaminase.	0.654
C807_00634	C807_00263	C807_00634	C807_00263	Hypothetical protein; Belongs to the 5'-nucleotidase family.	C_GCAxxG_C_C family protein.	0.469
C807_00634	C807_01096	C807_00634	C807_01096	Hypothetical protein; Belongs to the 5'-nucleotidase family.	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.929
C807_00634	C807_03200	C807_00634	C807_03200	Hypothetical protein; Belongs to the 5'-nucleotidase family.	dCMP deaminase.	0.934
C807_00634	thyA	C807_00634	C807_01670	Hypothetical protein; Belongs to the 5'-nucleotidase family.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.936
C807_00634	tmk	C807_00634	C807_03013	Hypothetical protein; Belongs to the 5'-nucleotidase family.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.936
C807_00634	upp	C807_00634	C807_03201	Hypothetical protein; Belongs to the 5'-nucleotidase family.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.933
C807_01096	C807_00263	C807_01096	C807_00263	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	C_GCAxxG_C_C family protein.	0.549
C807_01096	C807_00634	C807_01096	C807_00634	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Hypothetical protein; Belongs to the 5'-nucleotidase family.	0.929
C807_01096	C807_03200	C807_01096	C807_03200	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	dCMP deaminase.	0.962
C807_01096	cmk	C807_01096	C807_00602	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Cytidylate kinase.	0.540
C807_01096	thyA	C807_01096	C807_01670	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.988
C807_01096	tmk	C807_01096	C807_03013	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.949
C807_03200	C807_00263	C807_03200	C807_00263	dCMP deaminase.	C_GCAxxG_C_C family protein.	0.616