C807_03859 protein (Lachnospiraceae bacterium 284)

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Score

C807_03859

23S rRNA (-C5)-methyltransferase. (286 aa)

Predicted Functional Partners:

C807_03858

0.507

C807_01096

0.493

C807_01943

0.475

folD

0.467

glyA

0.456

C807_02239

0.456

Your Current Organism:

Lachnospiraceae bacterium 284

NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C807_01096	C807_03858	C807_01096	C807_03858	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Hypothetical protein.	0.543
C807_01096	C807_03859	C807_01096	C807_03859	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	23S rRNA (-C5)-methyltransferase.	0.493
C807_01943	C807_03859	C807_01943	C807_03859	FolC protein; Belongs to the folylpolyglutamate synthase family.	23S rRNA (-C5)-methyltransferase.	0.475
C807_01943	folD	C807_01943	C807_01288	FolC protein; Belongs to the folylpolyglutamate synthase family.	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.573
C807_01943	glyA	C807_01943	C807_01892	FolC protein; Belongs to the folylpolyglutamate synthase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.662
C807_02239	C807_03859	C807_02239	C807_03859	Hypothetical protein.	23S rRNA (-C5)-methyltransferase.	0.456
C807_02239	folD	C807_02239	C807_01288	Hypothetical protein.	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.866
C807_03858	C807_01096	C807_03858	C807_01096	Hypothetical protein.	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.543
C807_03858	C807_03859	C807_03858	C807_03859	Hypothetical protein.	23S rRNA (-C5)-methyltransferase.	0.507
C807_03859	C807_01096	C807_03859	C807_01096	23S rRNA (-C5)-methyltransferase.	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.493
C807_03859	C807_01943	C807_03859	C807_01943	23S rRNA (-C5)-methyltransferase.	FolC protein; Belongs to the folylpolyglutamate synthase family.	0.475
C807_03859	C807_02239	C807_03859	C807_02239	23S rRNA (-C5)-methyltransferase.	Hypothetical protein.	0.456
C807_03859	C807_03858	C807_03859	C807_03858	23S rRNA (-C5)-methyltransferase.	Hypothetical protein.	0.507
C807_03859	folD	C807_03859	C807_01288	23S rRNA (-C5)-methyltransferase.	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.467
C807_03859	glyA	C807_03859	C807_01892	23S rRNA (-C5)-methyltransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.456
folD	C807_01943	C807_01288	C807_01943	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	FolC protein; Belongs to the folylpolyglutamate synthase family.	0.573
folD	C807_02239	C807_01288	C807_02239	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Hypothetical protein.	0.866
folD	C807_03859	C807_01288	C807_03859	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	23S rRNA (-C5)-methyltransferase.	0.467
folD	glyA	C807_01288	C807_01892	FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.993
glyA	C807_01943	C807_01892	C807_01943	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	FolC protein; Belongs to the folylpolyglutamate synthase family.	0.662