close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C807_04019DNA (cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (666 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.938
C807_03532
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.929
C807_02127
DNA (cytosine-5-)-methyltransferase.
 
 
0.808
C807_01437
DNA (cytosine-5-)-methyltransferase; Overlaps another CDS with the same product name.
 
 
0.807
C807_04020
Hypothetical protein.
 
     0.802
C807_04017
Hypothetical protein; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.797
C807_04021
Hypothetical protein.
 
     0.792
C807_02556
Adenosylhomocysteinase.
     
 0.762
C807_01438
DNA (cytosine-5-)-methyltransferase; Overlaps another CDS with the same product name.
 
 
0.734
C807_00038
DNA (cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
     0.656
Your Current Organism:
Lachnospiraceae bacterium 284
NCBI taxonomy Id: 397287
Other names: L. bacterium 28-4, Lachnospiraceae bacterium 28-4
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.