rnhA protein (Lachnospiraceae bacterium 31) - STRING interaction network

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Score

rnhA

Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (157 aa)

Predicted Functional Partners:

polA

0.924

C806_04452

0.924

rnhB

0.841

C806_01135

0.786

C806_01074

0.753

C806_00453

0.720

C806_01037

0.720

C806_03901

0.720

prfB

0.705

C806_00322

0.704

Your Current Organism:

Lachnospiraceae bacterium 31

NCBI taxonomy Id: 397288
Other names: L. bacterium 3-1, Lachnospiraceae bacterium 3-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C806_00322	C806_00453	C806_00322	C806_00453	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Single-stranded DNA-binding protein.	0.840
C806_00322	C806_01037	C806_00322	C806_01037	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Hypothetical protein.	0.773
C806_00322	C806_01135	C806_00322	C806_01135	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.808
C806_00322	C806_03901	C806_00322	C806_03901	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Single-stranded DNA-binding protein.	0.815
C806_00322	polA	C806_00322	C806_03839	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.991
C806_00322	rnhA	C806_00322	C806_01075	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.704
C806_00322	rnhB	C806_00322	C806_04444	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.921
C806_00453	C806_00322	C806_00453	C806_00322	Single-stranded DNA-binding protein.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.840
C806_00453	C806_01037	C806_00453	C806_01037	Single-stranded DNA-binding protein.	Hypothetical protein.	0.611
C806_00453	polA	C806_00453	C806_03839	Single-stranded DNA-binding protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.615
C806_00453	prfB	C806_00453	C806_01770	Single-stranded DNA-binding protein.	Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	0.579
C806_00453	rnhA	C806_00453	C806_01075	Single-stranded DNA-binding protein.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.720
C806_01037	C806_00322	C806_01037	C806_00322	Hypothetical protein.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.773
C806_01037	C806_00453	C806_01037	C806_00453	Hypothetical protein.	Single-stranded DNA-binding protein.	0.611
C806_01037	C806_03901	C806_01037	C806_03901	Hypothetical protein.	Single-stranded DNA-binding protein.	0.611
C806_01037	polA	C806_01037	C806_03839	Hypothetical protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.512
C806_01037	prfB	C806_01037	C806_01770	Hypothetical protein.	Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	0.579
C806_01037	rnhA	C806_01037	C806_01075	Hypothetical protein.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.720
C806_01074	rnhA	C806_01074	C806_01075	Hypothetical protein.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.753
C806_01135	C806_00322	C806_01135	C806_00322	dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.808