| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C806_00197 | C806_01052 | C806_00197 | C806_01052 | Stage V sporulation protein AD. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.846 |
| C806_00197 | C806_01079 | C806_00197 | C806_01079 | Stage V sporulation protein AD. | Stage III sporulation protein AA. | 0.795 |
| C806_00197 | C806_01912 | C806_00197 | C806_01912 | Stage V sporulation protein AD. | Stage II sporulation protein E. | 0.772 |
| C806_00197 | C806_01916 | C806_00197 | C806_01916 | Stage V sporulation protein AD. | Sporulation protein YabP. | 0.773 |
| C806_00197 | C806_02428 | C806_00197 | C806_02428 | Stage V sporulation protein AD. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.777 |
| C806_00197 | C806_02430 | C806_00197 | C806_02430 | Stage V sporulation protein AD. | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.774 |
| C806_00197 | C806_03210 | C806_00197 | C806_03210 | Stage V sporulation protein AD. | Stage V sporulation protein T. | 0.824 |
| C806_00197 | C806_03314 | C806_00197 | C806_03314 | Stage V sporulation protein AD. | Stage II sporulation protein R. | 0.778 |
| C806_00197 | gpr | C806_00197 | C806_02347 | Stage V sporulation protein AD. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.938 |
| C806_00197 | spoIIAB | C806_00197 | C806_00214 | Stage V sporulation protein AD. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.824 |
| C806_01052 | C806_00197 | C806_01052 | C806_00197 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage V sporulation protein AD. | 0.846 |
| C806_01052 | C806_01079 | C806_01052 | C806_01079 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AA. | 0.840 |
| C806_01052 | C806_01912 | C806_01052 | C806_01912 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein E. | 0.871 |
| C806_01052 | C806_01916 | C806_01052 | C806_01916 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Sporulation protein YabP. | 0.732 |
| C806_01052 | C806_02428 | C806_01052 | C806_02428 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.861 |
| C806_01052 | C806_02430 | C806_01052 | C806_02430 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.849 |
| C806_01052 | C806_03210 | C806_01052 | C806_03210 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage V sporulation protein T. | 0.835 |
| C806_01052 | C806_03314 | C806_01052 | C806_03314 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein R. | 0.845 |
| C806_01052 | gpr | C806_01052 | C806_02347 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.839 |
| C806_01052 | spoIIAB | C806_01052 | C806_00214 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.862 |