C810_00286 protein (Lachnospiraceae bacterium A2)

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Score

C810_00286

Exonuclease SbcC. (941 aa)

Predicted Functional Partners:

sbcD

0.998

C810_00371

0.952

polA

0.939

uvrC

0.840

uvrB

0.807

recA

0.757

uvrA

0.723

mfd

0.697

C810_01790

0.695

frr

0.654

Your Current Organism:

Lachnospiraceae bacterium A2

NCBI taxonomy Id: 397290
Other names: L. bacterium A2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C810_00286	C810_00371	C810_00286	C810_00371	Exonuclease SbcC.	Hypothetical protein.	0.952
C810_00286	C810_01790	C810_00286	C810_01790	Exonuclease SbcC.	Maltose/maltodextrin transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.695
C810_00286	frr	C810_00286	C810_02891	Exonuclease SbcC.	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	0.654
C810_00286	mfd	C810_00286	C810_00711	Exonuclease SbcC.	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.697
C810_00286	polA	C810_00286	C810_01905	Exonuclease SbcC.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.939
C810_00286	recA	C810_00286	C810_02108	Exonuclease SbcC.	Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.757
C810_00286	sbcD	C810_00286	C810_00285	Exonuclease SbcC.	Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.998
C810_00286	uvrA	C810_00286	C810_03780	Exonuclease SbcC.	Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.	0.723
C810_00286	uvrB	C810_00286	C810_03778	Exonuclease SbcC.	UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]	0.807
C810_00286	uvrC	C810_00286	C810_04336	Exonuclease SbcC.	Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.840
C810_00371	C810_00286	C810_00371	C810_00286	Hypothetical protein.	Exonuclease SbcC.	0.952
C810_00371	mfd	C810_00371	C810_00711	Hypothetical protein.	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.727
C810_00371	polA	C810_00371	C810_01905	Hypothetical protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.973
C810_00371	recA	C810_00371	C810_02108	Hypothetical protein.	Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.800
C810_00371	uvrA	C810_00371	C810_03780	Hypothetical protein.	Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.	0.736
C810_00371	uvrB	C810_00371	C810_03778	Hypothetical protein.	UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]	0.688
C810_00371	uvrC	C810_00371	C810_04336	Hypothetical protein.	Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.590
C810_01790	C810_00286	C810_01790	C810_00286	Maltose/maltodextrin transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	Exonuclease SbcC.	0.695
frr	C810_00286	C810_02891	C810_00286	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Exonuclease SbcC.	0.654
frr	polA	C810_02891	C810_01905	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.429