Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C810_01249Hypothetical protein. (230 aa)    
Predicted Functional Partners:
C810_01248
Hypothetical protein.
 
    0.913
C810_01246
Hypothetical protein.
 
    0.855
C810_01250
Hypothetical protein.
       0.812
C810_01245
Hypothetical protein.
 
    0.760
C810_01251
Hypothetical protein.
       0.675
C810_03916
methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
      0.661
C810_01244
DNA (cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
     0.646
C810_00702
Ribose-phosphate diphosphokinase.
    
  0.586
C810_01254
HK97 family phage portal protein.
 
    0.578
C810_01256
HK97 family phage major capsid protein.
 
  
 0.566
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
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