| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C810_01572 | C810_01574 | C810_01572 | C810_01574 | Hypothetical protein. | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.449 |
| C810_01572 | C810_01575 | C810_01572 | C810_01575 | Hypothetical protein. | Hypothetical protein. | 0.482 |
| C810_01572 | thyA | C810_01572 | C810_01573 | Hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.487 |
| C810_01574 | C810_01572 | C810_01574 | C810_01572 | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein. | 0.449 |
| C810_01574 | C810_01575 | C810_01574 | C810_01575 | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein. | 0.663 |
| C810_01574 | C810_01576 | C810_01574 | C810_01576 | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein. | 0.572 |
| C810_01574 | thyA | C810_01574 | C810_01573 | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| C810_01575 | C810_01572 | C810_01575 | C810_01572 | Hypothetical protein. | Hypothetical protein. | 0.482 |
| C810_01575 | C810_01574 | C810_01575 | C810_01574 | Hypothetical protein. | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.663 |
| C810_01575 | C810_01576 | C810_01575 | C810_01576 | Hypothetical protein. | Hypothetical protein. | 0.682 |
| C810_01575 | C810_02192 | C810_01575 | C810_02192 | Hypothetical protein. | Malate dehydrogenase (oxaloacetate-decarboxylating). | 0.709 |
| C810_01575 | thyA | C810_01575 | C810_01573 | Hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.606 |
| C810_01576 | C810_01574 | C810_01576 | C810_01574 | Hypothetical protein. | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.572 |
| C810_01576 | C810_01575 | C810_01576 | C810_01575 | Hypothetical protein. | Hypothetical protein. | 0.682 |
| C810_01576 | thyA | C810_01576 | C810_01573 | Hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.523 |
| C810_02192 | C810_01575 | C810_02192 | C810_01575 | Malate dehydrogenase (oxaloacetate-decarboxylating). | Hypothetical protein. | 0.709 |
| thyA | C810_01572 | C810_01573 | C810_01572 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Hypothetical protein. | 0.487 |
| thyA | C810_01574 | C810_01573 | C810_01574 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.999 |
| thyA | C810_01575 | C810_01573 | C810_01575 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Hypothetical protein. | 0.606 |
| thyA | C810_01576 | C810_01573 | C810_01576 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Hypothetical protein. | 0.523 |
