Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C810_01871Hypothetical protein. (427 aa)    
Predicted Functional Partners:
C810_01867
Glycolate oxidase, subunit GlcD.
 
  
 0.976
C810_04041
Hypothetical protein.
 
  
 0.928
C810_04948
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
    
 0.927
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
     
 0.918
C810_00764
Hypothetical protein.
 
  
 0.905
C810_01868
Hypothetical protein.
 
  
 0.895
C810_01869
Hypothetical protein.
 
  
 0.856
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.801
C810_01866
Lactate permease (LctP) family transporter; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
   
 0.781
C810_01870
butyryl-CoA dehydrogenase.
     
 0.776
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
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