Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (1134 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 0.995
C810_02224
Hypothetical protein.
  
 0.987
C810_02041
Hypothetical protein.
   
 0.958
sepF
Cell division inhibitor SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
 
 0.886
C810_04287
Hypothetical protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 0.862
C810_01907
Hypothetical protein.
       0.839
C810_01828
Hypothetical protein.
  
 
 0.830
C810_00737
Cell division protein FtsL.
  
 
 0.822
C810_02223
Cell division protein FtsW; Belongs to the SEDS family.
  
 0.809
C810_02485
Hypothetical protein; Belongs to the SEDS family.
  
 0.809
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
Server load: low (24%) [HD]