| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C810_00214 | C810_02180 | C810_00214 | C810_02180 | Hypothetical protein; Belongs to the 5'-nucleotidase family. | Epoxide hydrolase domain-like phosphatase. | 0.762 |
| C810_00214 | guaA | C810_00214 | C810_00804 | Hypothetical protein; Belongs to the 5'-nucleotidase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.905 |
| C810_00214 | guaB | C810_00214 | C810_04425 | Hypothetical protein; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.976 |
| C810_00214 | purA | C810_00214 | C810_02179 | Hypothetical protein; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.907 |
| C810_00214 | pyrH | C810_00214 | C810_02892 | Hypothetical protein; Belongs to the 5'-nucleotidase family. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.884 |
| C810_00382 | C810_02180 | C810_00382 | C810_02180 | Hypothetical protein; Converts alpha-aldose to the beta-anomer. | Epoxide hydrolase domain-like phosphatase. | 0.755 |
| C810_02180 | C810_00214 | C810_02180 | C810_00214 | Epoxide hydrolase domain-like phosphatase. | Hypothetical protein; Belongs to the 5'-nucleotidase family. | 0.762 |
| C810_02180 | C810_00382 | C810_02180 | C810_00382 | Epoxide hydrolase domain-like phosphatase. | Hypothetical protein; Converts alpha-aldose to the beta-anomer. | 0.755 |
| C810_02180 | C810_02274 | C810_02180 | C810_02274 | Epoxide hydrolase domain-like phosphatase. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.753 |
| C810_02180 | C810_02335 | C810_02180 | C810_02335 | Epoxide hydrolase domain-like phosphatase. | Hypothetical protein. | 0.804 |
| C810_02180 | C810_03944 | C810_02180 | C810_03944 | Epoxide hydrolase domain-like phosphatase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.942 |
| C810_02180 | glyA | C810_02180 | C810_01758 | Epoxide hydrolase domain-like phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.778 |
| C810_02180 | guaA | C810_02180 | C810_00804 | Epoxide hydrolase domain-like phosphatase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.925 |
| C810_02180 | guaB | C810_02180 | C810_04425 | Epoxide hydrolase domain-like phosphatase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.938 |
| C810_02180 | purA | C810_02180 | C810_02179 | Epoxide hydrolase domain-like phosphatase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.760 |
| C810_02180 | pyrH | C810_02180 | C810_02892 | Epoxide hydrolase domain-like phosphatase. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.755 |
| C810_02274 | C810_02180 | C810_02274 | C810_02180 | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | Epoxide hydrolase domain-like phosphatase. | 0.753 |
| C810_02274 | C810_03944 | C810_02274 | C810_03944 | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.671 |
| C810_02274 | guaA | C810_02274 | C810_00804 | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.555 |
| C810_02274 | guaB | C810_02274 | C810_04425 | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.614 |
