C810_02733 protein (Lachnospiraceae bacterium A2)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Lachnospiraceae bacterium A2

NCBI taxonomy Id: 397290
Other names: L. bacterium A2

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C810_02731	C810_02733	C810_02731	C810_02733	Hypothetical protein.	RNA-binding protein.	0.919
C810_02731	C810_02736	C810_02731	C810_02736	Hypothetical protein.	Hypothetical protein.	0.524
C810_02731	aroE	C810_02731	C810_02115	Hypothetical protein.	Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).	0.690
C810_02731	nadD	C810_02731	C810_02732	Hypothetical protein.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.998
C810_02731	obg	C810_02731	C810_02734	Hypothetical protein.	GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	0.740
C810_02731	rplU	C810_02731	C810_02737	Hypothetical protein.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.509
C810_02731	rpmA	C810_02731	C810_02735	Hypothetical protein.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.521
C810_02731	rsfS	C810_02731	C810_02730	Hypothetical protein.	Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.973
C810_02733	C810_02731	C810_02733	C810_02731	RNA-binding protein.	Hypothetical protein.	0.919
C810_02733	C810_02736	C810_02733	C810_02736	RNA-binding protein.	Hypothetical protein.	0.622
C810_02733	aroE	C810_02733	C810_02115	RNA-binding protein.	Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).	0.647
C810_02733	infA	C810_02733	C810_00320	RNA-binding protein.	Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.	0.613
C810_02733	nadD	C810_02733	C810_02732	RNA-binding protein.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.969
C810_02733	obg	C810_02733	C810_02734	RNA-binding protein.	GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	0.835
C810_02733	rplK	C810_02733	C810_03360	RNA-binding protein.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.803
C810_02733	rplU	C810_02733	C810_02737	RNA-binding protein.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.578
C810_02733	rpmA	C810_02733	C810_02735	RNA-binding protein.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.576
C810_02733	rsfS	C810_02733	C810_02730	RNA-binding protein.	Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.923
C810_02736	C810_02731	C810_02736	C810_02731	Hypothetical protein.	Hypothetical protein.	0.524
C810_02736	C810_02733	C810_02736	C810_02733	Hypothetical protein.	RNA-binding protein.	0.622