Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C810_03049[FeFe] hydrogenase, group A. (565 aa)    
Predicted Functional Partners:
C810_03050
NADH-quinone oxidoreductase subunit F.
 
 
 0.999
C810_03051
NADH-quinone oxidoreductase subunit E.
 0.999
C810_04948
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
 
 
 0.918
C810_03918
Hypothetical protein.
   
 0.819
C810_00213
Hypothetical protein.
   
 0.803
C810_02056
Glutamate synthase (NADPH), homotetrameric.
  
 0.773
rnfB
Electron transport complex, rnfabcdge type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
    
 0.772
C810_04343
[FeFe] hydrogenase H-cluster maturation GTPase HydF.
 
   
 0.770
C810_00215
[FeFe] hydrogenase H-cluster radical SAM maturase HydE.
 
  
 0.747
C810_04682
Ferredoxin.
   
 0.741
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
Server load: low (14%) [HD]