Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C810_03243Acetolactate synthase I/II/III large subunit. (144 aa)    
Predicted Functional Partners:
C810_03242
Hypothetical protein.
     0.992
C810_03244
Acetolactate synthase I/II/III large subunit.
     0.989
C810_01590
Acetolactate synthase, small subunit.
 
 0.973
C810_01312
Acetolactate synthase, small subunit.
 
 0.969
C810_03241
Hypothetical protein.
 
 0.964
C810_02976
Acetolactate synthase, small subunit.
 
 0.961
C810_04948
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.959
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.936
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 0.902
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.836
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
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