C810_03382 protein (Lachnospiraceae bacterium A2)

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Score

C810_03382

Hypothetical protein. (162 aa)

Predicted Functional Partners:

C810_01536

0.765

thiE

0.741

thiE-2

0.741

C810_02257

0.730

iscS

0.730

C810_01298

0.695

thiC

0.677

mnmA

0.655

thiI

0.649

C810_00776

0.644

Your Current Organism:

Lachnospiraceae bacterium A2

NCBI taxonomy Id: 397290
Other names: L. bacterium A2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C810_00776	C810_01536	C810_00776	C810_01536	Phosphomethylpyrimidine kinase.	Hypothetical protein; Belongs to the TtcA family.	0.479
C810_00776	C810_03382	C810_00776	C810_03382	Phosphomethylpyrimidine kinase.	Hypothetical protein.	0.644
C810_00776	thiC	C810_00776	C810_00772	Phosphomethylpyrimidine kinase.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.	0.985
C810_00776	thiE	C810_00776	C810_00775	Phosphomethylpyrimidine kinase.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.997
C810_00776	thiE-2	C810_00776	C810_01306	Phosphomethylpyrimidine kinase.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.998
C810_01298	C810_03382	C810_01298	C810_03382	Hypothetical protein.	Hypothetical protein.	0.695
C810_01536	C810_00776	C810_01536	C810_00776	Hypothetical protein; Belongs to the TtcA family.	Phosphomethylpyrimidine kinase.	0.479
C810_01536	C810_02257	C810_01536	C810_02257	Hypothetical protein; Belongs to the TtcA family.	Hypothetical protein.	0.895
C810_01536	C810_03382	C810_01536	C810_03382	Hypothetical protein; Belongs to the TtcA family.	Hypothetical protein.	0.765
C810_01536	iscS	C810_01536	C810_04119	Hypothetical protein; Belongs to the TtcA family.	Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.895
C810_01536	mnmA	C810_01536	C810_04117	Hypothetical protein; Belongs to the TtcA family.	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.	0.838
C810_01536	thiC	C810_01536	C810_00772	Hypothetical protein; Belongs to the TtcA family.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.	0.442
C810_01536	thiE	C810_01536	C810_00775	Hypothetical protein; Belongs to the TtcA family.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.407
C810_01536	thiE-2	C810_01536	C810_01306	Hypothetical protein; Belongs to the TtcA family.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.407
C810_01536	thiI	C810_01536	C810_02258	Hypothetical protein; Belongs to the TtcA family.	tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.803
C810_02257	C810_01536	C810_02257	C810_01536	Hypothetical protein.	Hypothetical protein; Belongs to the TtcA family.	0.895
C810_02257	C810_03382	C810_02257	C810_03382	Hypothetical protein.	Hypothetical protein.	0.730
C810_02257	iscS	C810_02257	C810_04119	Hypothetical protein.	Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.940
C810_02257	mnmA	C810_02257	C810_04117	Hypothetical protein.	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.	0.909
C810_02257	thiI	C810_02257	C810_02258	Hypothetical protein.	tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.991