Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C810_03471Hypothetical protein. (484 aa)    
Predicted Functional Partners:
C810_02957
Chorismate mutase.
    
 0.772
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.756
C810_04773
Glutamine synthetase, type I.
    
 0.752
C810_00348
Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.748
C810_00464
Aminotransferase.
   
 0.748
C810_05259
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
     
  0.732
C810_01847
Glutamate synthase (ferredoxin).
   
 
  0.730
C810_05108
Hypothetical protein.
  
 
 0.650
C810_01867
Glycolate oxidase, subunit GlcD.
    
 0.623
C810_04051
YbgI/family dinuclear metal center protein.
   
    0.605
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
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