C810_04062 protein (Lachnospiraceae bacterium A2)

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Score

C810_04062

Exodeoxyribonuclease III (xth). (258 aa)

Predicted Functional Partners:

polA

0.999

nth

0.998

C810_04846

0.996

nth-2

0.995

C810_04244

0.991

ung

0.979

C810_00779

0.964

tadA

0.954

nfo

0.938

birA

0.934

Your Current Organism:

Lachnospiraceae bacterium A2

NCBI taxonomy Id: 397290
Other names: L. bacterium A2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C810_00779	C810_04062	C810_00779	C810_04062	DNA-deoxyinosine glycosylase.	Exodeoxyribonuclease III (xth).	0.964
C810_00779	C810_04244	C810_00779	C810_04244	DNA-deoxyinosine glycosylase.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.861
C810_04062	C810_00779	C810_04062	C810_00779	Exodeoxyribonuclease III (xth).	DNA-deoxyinosine glycosylase.	0.964
C810_04062	C810_04244	C810_04062	C810_04244	Exodeoxyribonuclease III (xth).	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.991
C810_04062	C810_04846	C810_04062	C810_04846	Exodeoxyribonuclease III (xth).	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.996
C810_04062	birA	C810_04062	C810_04646	Exodeoxyribonuclease III (xth).	biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	0.934
C810_04062	nfo	C810_04062	C810_03136	Exodeoxyribonuclease III (xth).	Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.938
C810_04062	nth	C810_04062	C810_00456	Exodeoxyribonuclease III (xth).	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.998
C810_04062	nth-2	C810_04062	C810_03469	Exodeoxyribonuclease III (xth).	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.995
C810_04062	polA	C810_04062	C810_01905	Exodeoxyribonuclease III (xth).	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.999
C810_04062	tadA	C810_04062	C810_03293	Exodeoxyribonuclease III (xth).	Hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.954
C810_04062	ung	C810_04062	C810_01913	Exodeoxyribonuclease III (xth).	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.979
C810_04244	C810_00779	C810_04244	C810_00779	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA-deoxyinosine glycosylase.	0.861
C810_04244	C810_04062	C810_04244	C810_04062	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Exodeoxyribonuclease III (xth).	0.991
C810_04244	C810_04846	C810_04244	C810_04846	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.736
C810_04244	birA	C810_04244	C810_04646	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	0.472
C810_04244	nth	C810_04244	C810_00456	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.580
C810_04244	nth-2	C810_04244	C810_03469	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.587
C810_04846	C810_04062	C810_04846	C810_04062	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III (xth).	0.996
C810_04846	C810_04244	C810_04846	C810_04244	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.736