node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C810_02341 | C810_04217 | C810_02341 | C810_04217 | DNA protecting protein DprA. | single-stranded-DNA-specific exonuclease RecJ. | 0.698 |
C810_02341 | C810_04698 | C810_02341 | C810_04698 | DNA protecting protein DprA. | Single-stranded DNA-binding protein. | 0.512 |
C810_02341 | C810_04846 | C810_02341 | C810_04846 | DNA protecting protein DprA. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.558 |
C810_02341 | mutS | C810_02341 | C810_02699 | DNA protecting protein DprA. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.400 |
C810_02341 | secF | C810_02341 | C810_04170 | DNA protecting protein DprA. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.539 |
C810_02341 | topA | C810_02341 | C810_02342 | DNA protecting protein DprA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.909 |
C810_04217 | C810_02341 | C810_04217 | C810_02341 | single-stranded-DNA-specific exonuclease RecJ. | DNA protecting protein DprA. | 0.698 |
C810_04217 | C810_04698 | C810_04217 | C810_04698 | single-stranded-DNA-specific exonuclease RecJ. | Single-stranded DNA-binding protein. | 0.599 |
C810_04217 | C810_04846 | C810_04217 | C810_04846 | single-stranded-DNA-specific exonuclease RecJ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.620 |
C810_04217 | mutL | C810_04217 | C810_02702 | single-stranded-DNA-specific exonuclease RecJ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.619 |
C810_04217 | mutS | C810_04217 | C810_02699 | single-stranded-DNA-specific exonuclease RecJ. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.659 |
C810_04217 | priA | C810_04217 | C810_05078 | single-stranded-DNA-specific exonuclease RecJ. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.709 |
C810_04217 | secF | C810_04217 | C810_04170 | single-stranded-DNA-specific exonuclease RecJ. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.638 |
C810_04217 | topA | C810_04217 | C810_02342 | single-stranded-DNA-specific exonuclease RecJ. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.747 |
C810_04217 | topB | C810_04217 | C810_00787 | single-stranded-DNA-specific exonuclease RecJ. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.686 |
C810_04217 | truA-2 | C810_04217 | C810_04218 | single-stranded-DNA-specific exonuclease RecJ. | tRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.621 |
C810_04698 | C810_02341 | C810_04698 | C810_02341 | Single-stranded DNA-binding protein. | DNA protecting protein DprA. | 0.512 |
C810_04698 | C810_04217 | C810_04698 | C810_04217 | Single-stranded DNA-binding protein. | single-stranded-DNA-specific exonuclease RecJ. | 0.599 |
C810_04698 | C810_04846 | C810_04698 | C810_04846 | Single-stranded DNA-binding protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.445 |
C810_04698 | priA | C810_04698 | C810_05078 | Single-stranded DNA-binding protein. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.850 |