| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C810_00702 | pyrB | C810_00702 | C810_04047 | Ribose-phosphate diphosphokinase. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.466 |
| C810_00702 | pyrE | C810_00702 | C810_04263 | Ribose-phosphate diphosphokinase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.907 |
| C810_00702 | pyrF | C810_00702 | C810_04267 | Ribose-phosphate diphosphokinase. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.695 |
| C810_02055 | carA | C810_02055 | C810_00986 | ferredoxin-NADP+ reductase. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.925 |
| C810_02055 | pyrB | C810_02055 | C810_04047 | ferredoxin-NADP+ reductase. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.911 |
| C810_02055 | pyrC | C810_02055 | C810_04268 | ferredoxin-NADP+ reductase. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.903 |
| C810_02055 | pyrD | C810_02055 | C810_01213 | ferredoxin-NADP+ reductase. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.981 |
| C810_02055 | pyrD-2 | C810_02055 | C810_04265 | ferredoxin-NADP+ reductase. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.981 |
| C810_02055 | pyrE | C810_02055 | C810_04263 | ferredoxin-NADP+ reductase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.929 |
| C810_02055 | pyrF | C810_02055 | C810_04267 | ferredoxin-NADP+ reductase. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.929 |
| C810_04261 | pyrE | C810_04261 | C810_04263 | Hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.820 |
| carA | C810_02055 | C810_00986 | C810_02055 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | ferredoxin-NADP+ reductase. | 0.925 |
| carA | pyrB | C810_00986 | C810_04047 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrC | C810_00986 | C810_04268 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
| carA | pyrD | C810_00986 | C810_01213 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.902 |
| carA | pyrD-2 | C810_00986 | C810_04265 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.902 |
| carA | pyrE | C810_00986 | C810_04263 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.959 |
| carA | pyrF | C810_00986 | C810_04267 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.940 |
| carA | pyrK | C810_00986 | C810_04266 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.976 |
| pyrB | C810_00702 | C810_04047 | C810_00702 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Ribose-phosphate diphosphokinase. | 0.466 |