close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C810_04424Trehalose operon repressor. (240 aa)    
Predicted Functional Partners:
C810_04948
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
    
  0.787
C810_04423
PTS system, trehalose-specific IIBC component.
 
   
 0.759
C810_03154
PTS system, glucose subfamily, IIA component.
 
  
 0.655
C810_01180
PTS system, sucrose-specific IIBC component.
 
  
 0.644
C810_04871
Hypothetical protein.
  
     0.628
C810_04294
PTS system, sucrose-specific IIBC component.
 
  
 0.615
C810_01879
PTS system, glucose subfamily, IIA component.
 
  
 0.599
C810_02296
N-acetylglucosamine-6-phosphate deacetylase.
  
  
 0.532
C810_02306
PTS system, glucose subfamily, IIA component.
 
  
 0.516
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.489
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.