STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C810_04429Stage V sporulation protein AE. (118 aa)    
Predicted Functional Partners:
C810_04430
Stage V sporulation protein AD.
 
  
 0.978
C810_04470
Stage V sporulation protein AC.
 
  
 0.928
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
     0.826
C810_04476
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
     0.822
gpr
GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.786
C810_00995
Hypothetical protein.
  
  
 0.781
C810_02135
Stage IV sporulation protein B.
  
   
 0.780
C810_02091
Stage III sporulation protein AA.
  
   
 0.779
C810_00368
Stage V sporulation protein T.
  
    0.776
C810_02080
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.774
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.