STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABAnti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (143 aa)    
Predicted Functional Partners:
C810_04476
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.998
C810_05119
Hypothetical protein.
  
 
 0.982
C810_00216
[FeFe] hydrogenase H-cluster radical SAM maturase HydG.
   
    0.949
C810_02344
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.949
C810_02348
Flagellar motor switch protein FliG.
   
    0.949
C810_02352
Hypothetical protein.
   
    0.949
C810_02358
Chemotaxis protein MotA.
   
    0.949
C810_00738
Stage II sporulation protein E.
  
  
 0.901
C810_04470
Stage V sporulation protein AC.
 
   
 0.891
C810_04474
RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.888
Your Current Organism:
Lachnospiraceae bacterium A2
NCBI taxonomy Id: 397290
Other names: L. bacterium A2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.