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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa)    
Predicted Functional Partners:
C804_06077
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.991
C804_05599
Citrate synthase; Belongs to the citrate synthase family.
  
 0.989
C804_04299
Hypothetical protein.
  
 
 0.960
C804_00210
Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.948
C804_01468
Hydrolyase, tartrate alpha subunit/fumarate domain-containing protein, Fe-S type.
  
 
 0.935
atpA
ATP synthase F1, alpha subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes f [...]
  
 0.932
C804_01222
Pyruvate ferredoxin oxidoreductase, beta subunit.
  
 
 0.928
C804_01467
Hydrolyase, tartrate beta subunit/fumarate domain-containing protein, Fe-S type.
  
 
 0.918
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.915
C804_01223
Hypothetical protein.
  
 
 0.905
Your Current Organism:
Lachnospiraceae bacterium A4
NCBI taxonomy Id: 397291
Other names: L. bacterium A4
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