C804_01239 protein (Lachnospiraceae bacterium A4)

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Score

C804_01239

single-stranded-DNA-specific exonuclease RecJ. (598 aa)

Predicted Functional Partners:

secD

0.815

C804_01240

0.773

C804_01241

0.762

priA

0.706

topA

0.681

C804_04816

0.669

C804_04056

0.653

C804_03143

0.631

mutL

0.604

C804_01412

0.584

Your Current Organism:

Lachnospiraceae bacterium A4

NCBI taxonomy Id: 397291
Other names: L. bacterium A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C804_01239	C804_01240	C804_01239	C804_01240	single-stranded-DNA-specific exonuclease RecJ.	Hypothetical protein.	0.773
C804_01239	C804_01241	C804_01239	C804_01241	single-stranded-DNA-specific exonuclease RecJ.	Hypothetical protein.	0.762
C804_01239	C804_01412	C804_01239	C804_01412	single-stranded-DNA-specific exonuclease RecJ.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.584
C804_01239	C804_03143	C804_01239	C804_03143	single-stranded-DNA-specific exonuclease RecJ.	comF family protein.	0.631
C804_01239	C804_04056	C804_01239	C804_04056	single-stranded-DNA-specific exonuclease RecJ.	RecQ family ATP-dependent DNA helicase.	0.653
C804_01239	C804_04816	C804_01239	C804_04816	single-stranded-DNA-specific exonuclease RecJ.	ATP-dependent DNA helicase RecQ.	0.669
C804_01239	mutL	C804_01239	C804_02146	single-stranded-DNA-specific exonuclease RecJ.	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.604
C804_01239	priA	C804_01239	C804_00476	single-stranded-DNA-specific exonuclease RecJ.	Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	0.706
C804_01239	secD	C804_01239	C804_01242	single-stranded-DNA-specific exonuclease RecJ.	Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.	0.815
C804_01239	topA	C804_01239	C804_00452	single-stranded-DNA-specific exonuclease RecJ.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.681
C804_01240	C804_01239	C804_01240	C804_01239	Hypothetical protein.	single-stranded-DNA-specific exonuclease RecJ.	0.773
C804_01240	C804_01241	C804_01240	C804_01241	Hypothetical protein.	Hypothetical protein.	0.762
C804_01240	secD	C804_01240	C804_01242	Hypothetical protein.	Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.	0.524
C804_01241	C804_01239	C804_01241	C804_01239	Hypothetical protein.	single-stranded-DNA-specific exonuclease RecJ.	0.762
C804_01241	C804_01240	C804_01241	C804_01240	Hypothetical protein.	Hypothetical protein.	0.762
C804_01241	secD	C804_01241	C804_01242	Hypothetical protein.	Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.	0.531
C804_01412	C804_01239	C804_01412	C804_01239	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	single-stranded-DNA-specific exonuclease RecJ.	0.584
C804_01412	C804_03143	C804_01412	C804_03143	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	comF family protein.	0.454
C804_01412	C804_04056	C804_01412	C804_04056	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	RecQ family ATP-dependent DNA helicase.	0.995
C804_01412	C804_04816	C804_01412	C804_04816	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	ATP-dependent DNA helicase RecQ.	0.877