Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
C804_01784ATP-binding cassette, subfamily B, bacterial. (587 aa)    
Predicted Functional Partners:
C804_01783
Hypothetical protein.
 
  
 
0.892
C804_02272
Hypothetical protein.
 
 
0.716
C804_02586
Polar amino acid transport system ATP-binding protein.
 
   
 
0.615
C804_04032
Hypothetical protein; Belongs to the heat shock protein 70 family.
  
  0.605
C804_01912
Hypothetical protein.
 
 
 
0.588
dnaK
Chaperone dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.581
C804_03699
Hypothetical protein.
    
  0.579
C804_02918
Hypothetical protein.
  
  0.574
atpA
ATP synthase F1, alpha subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes f [...]
   
  0.569
rpsB
30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
    
  0.567
Your Current Organism:
Lachnospiraceae bacterium A4
NCBI taxonomy Id: 397291
Other names: L. bacterium A4
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